Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

2013 Hepatology Research 43;11 (1125-1126)

Along with the westernization of lifestyles, the prevalence of nonalcoholic fatty liver disease (NAFLD) has been increasing around the world in recent years. The estimated number of patients with NAFLD has reached 80-100 million in the U.S.,1-3) and the corresponding number of patients in Japan has been estimated at 10-20 million. The prevalence of NAFLD and nonalcoholic steatohepatitis (NASH) is increasing and is becoming a major target disease not only in Western countries, but also in Japan. Not only NAFLD, but also hepatic steatosis is a common feature among patients with alcoholic liver disease (ALD) and those with hepatitis C viral infection. In patients with chronic hepatitis C, coexisting steatosis reportedly accelerates fibrosis progression and reduces the treatment response.4) Therefore, the ability to diagnose hepatic steatosis accurately is important for clinical evaluation.

Pubmed : 23607912