Longitudinal change of liver stiffness by transient elestography in chronic hepatitis B patients treated with nucleos(t)ide analogue
Jang W., Yu S. I., Sinn D. H., Park S. H., Park H., Park J. Y., Jeon T. J., Oh T. H., Shin W. C. and Choi W. C.
2014
Clinics and Research in Hepatology and Gastroenter 38;2 (195-200)
BACKGROUND: Liver stiffness measurement (LSM) by transient elastography is a non-invasive method to assess liver fibrosis. Decline in LSM value has been reported after antiviral treatment (AVT) using nucleos(t)ide analogues (NUCs) in chronic hepatitis B (CHB) patients, however, factors associated with changes in LSM during AVT remains unclear. METHODS: A total of 76 CHB patients who received AVT with NUCs and had serial LSM (median duration: 16 months, range: 12 to 35 months) during AVT were analyzed. Complete virological response (CVR) was defined when hepatitis B virus DNA level was undetectable by real-time PCR assay (
Pubmed : 24231289