Interim assessment of liver damage in patients with sickle cell disease using new non-invasive techniques

2017 British Journal of Haematology 176;4 (643-650)

We explored transient elastography (TE) and enhanced liver fibrosis (ELF ) score with standard markers of liver function to assess liver damage in 193 well patients with sickle cell disease (SCD). Patients with HbSS or HbSbeta0 thalassaemia (sickle cell anaemia, SCA; N = 134), had significantly higher TE results and ELF scores than those with HbSC (N = 49) disease (TE, 6.8 vs. 5.3, P

Pubmed : 27984631