Guidelines for the screening, care and treatment of persons with hepatitis C infection

2014 World Health Organization

Assessing the degree of liver fibrosis and cirrhosis: In resource-limited settings, it is suggested that aminotransferase/platelet ratio index (APRI) or FIB4 be used for the assessment of hepatic fibrosis rather than other noninvasive tests that require more resources such as elastography or FibroTest.
Conditional recommendation, low quality of evidence
Note: This recommendation was formulated assuming that liver biopsy was not a feasible option. FibroScan, which is more accurate than APRI and FIB4, may be preferable in settings where the equipment is available and the cost of the test is not a barrier to testing.