EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 2: Clinical applications

2013 Ultraschall in der Medizin 34, 3 (238-253)

[...] A difficulty with liver elastography is the proliferation of different methods which are likely not equivalent. This means that cut-off values are system-specific and cannot readily be compared across machines.
Transient elastography
Transient elastography (TE) is performed using the FibroScan (Echosens, Paris, France).
- TE can be used to assess the severity of liver fibrosis in patients with chronic viral hepatitis, provided that confounding factors are taken into account, and especially to distinguish patients with nil/mild fibrosis from those with significant fibrosis and to identify those with cirrhosis.
- TE is useful for assessment of liver fibrosis in patients with NAFLD, alcoholic liver diseases, and in patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus. Other types of chronic liver disease might also be investigated, but the evidence is more limited.
- TE is useful for assessment of liver fibrosis in patients with post-transplant recurrence of chronic hepatitis C.
- TE has some value for predicting the occurrence of complications of liver cirrhosis, portal hypertension, HCC and liver associated mortality. It cannot replace upper gastrointestinal endoscopy for identifying patient with varices.

Pubmed : 23605169