[Consensus document: Diagnosis usefulness of FibroScan]

2011 Societat Catalana de Digestologia (Catalan Society

Fibroscan enables to assess and to grade hepatic fibrosis for a wide range of chronic liver diseases, and primarily to detect cirrhosis. Its diagnosis accuracy has been established for chronic HCV patients, including recurrent HCV after liver transplantation, and chronic cholestatic diseases (primary biliary cirrhosis). It has been suggested that a cut-off value of 7.6 kPa identifies significant fibrosis, whereas a cut-off value of 14.6 kPa detects cirrhosis. It is recommended that results are interpreted by an experienced practitioner, who is well aware of this techniques characteristics and its limitations. Results may be influenced by clinical processes which modify the consistency of the liver, such as acute hepatitis with elevated necrosis, cardiac insufficiency with venous congestion and bile duct dilatation. It is also advisable to repeat the examination if the final values are sub-optimal, and to use another non-invasive method or to perform a liver biopsy when results appear to be inconsistent. Fibroscan is as reliable as serological markers to identify significant fibrosis, whereas it is more reliable than these to identify cirrhosis. This techniques main advantages are: its rapidity, easy use, reproducibility and possibility to repeat it as often as required in order to follow-up the patients.