[Comparison of the M and XL FibroScan((R)) probes to estimate liver stiffness by transient elastography]

2014 Gastroenterologia y hepatologia 37;4 (233-239)

The FibroScan((R)) XL probe has been specifically designed for obese patients to measure liver stiffness by transient elastography, but it has not been well tested in non-obese patients. The aim of this study was to compare the M and XL FibroScan((R)) probes in a series of unselected obese (body mass index above 30 kg/m(2)) and non-obese patients with chronic liver disease. Two hundred and fifty-four patients underwent a transient elastography examination with both the M and XL probes. The results obtained with the two probes were compared in the whole series and in obese (n=82) and non-obese (n=167) patients separately. The reliability of the examinations was assessed using the criteria defined by Castera et al. The proportion of reliable exams was significantly higher when the XL probe was used (83% versus 73%; P=.001). This significance was maintained in the group of obese patients (82% versus 55%; P<.001 but not in the non-obese patients versus despite a high correlation between stiffness values obtained with two probes p and concordance estimation of fibrosis alpha value: liver xl probe were significantly lower than those m both whole series kpa obese groups. conclusion transient elastography allows higher proportion reliable examinations patients. probe. class="article_links">

Pubmed : 24417906