[Clinical protocol on treatment of viral Hepatitis and co-infections: Management of patients chronically infected with Hepatitis C (genotype 1) and advanced fibrosis]


The Triple-therapy is approved exclusively for mono-infected patients with the HCV genotype 1 and with advanced fibrosis (METAVIR F3 and F4) or compensated cirrhosis (Child-Pugh ? 6). [...]
The priority to this new treatment is given to patients with high risk of disease progression and death, defined by the fibrosis degree F3 or F4*, or by less invasive evidences of hepatic cirrhosis. [...]
*Hepatic elastography, which could be equivalent to the referred METAVIR score.